Independent

 

31.“Nickel-catalyzed Difunctionalization of Allyl Moieties Using Organoboronic Acids and Halides with Divergent Regioselectivities," Li, W.; Boon, J. K.; Zhao, Y.* Chem. Sci. 2018, in press.

 

30.“Nine-Membered Benzofuran-Fused Heterocycles: Enantioselective Synthesis by Pd-Catalysis and Rearrangement via Transannular Bond Formation," Rong, Z.-Q.; Yang, L.-C.; Liu, S.; Yu, Z.; Wang, Y.-N.; Tan, Z. Y.; Huang, R.-Z.; Lan, Y.;* Zhao, Y.* J. Am. Chem. Soc. 2017, 139,15304-15307 (R.Z.Q. and Y.L.C. contributed equally).

 

29.“Catalyst-Enabled Scaffold Diversity: Highly Chemo- and Stereoselective Synthesis of Tricyclic Ketals and Triarylmethanes," Liao, J.-Y.; Ni, Q.; Zhao, Y. Org. Lett. 2017, 19, 4074-4077.

 

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28.“Three-Component Reactions of Isocyanoacetates, Amines and 3-Formylchromones Initiated by an Unexpected aza-Michael Addition," Liao, J.-Y.; Yap, W. J.; Wu, J.; Wong, M. W.;* Zhao, Y.* Chem. Commun. 2017, 53, 9067-9070.

 

27.“Enantioselective Synthesis of Tetrahydroquinolines Using Borrowing Hydrogen: Cooperative Catalysis by Achiral Iridacycle and Chiral Phosphoric Acid," Lim, C. S.; Quach, T. T.; Zhao, Y. Angew. Chem. Int. Ed. 2017, 56, 7176-7180 (VIP).

 

This article was featured in Synfacts.

 

26.“Divergent Reactivities in Fluoronation of Allylic Alcohols: Synthesis of Z-Fluoroalkenes via Carbon-Carbon Bond Cleavage," Liu, T.-L.; Wu, J.; Zhao, Y. Chem. Sci. 2017, 8, 3885-3890.

 

25.“Rhodium-Catalyzed Enantioselective Isomerization of Secondary Allylic Alcohols," Liu, T.-L.; Ng, T. W.; Zhao, Y. J. Am. Chem. Soc. 2017, 139, 3643-3646.

 

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24.“Construction of Nine-Membered Heterocycles through Palladium-Catalyzed Formal [5 + 4] Cycloaddition,” Yang, L.-C.; Rong, Z.-Q.; Wang, Y.-N.; Tan, Z. Y.; Wang, M. Zhao, Y. Angew. Chem. Int. Ed. 2017, 56, 2927-2931 (Y.L.C. and R.Z.Q. contributed equally).

 

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23.“Access to Enantiopure Triarylmethanes and 1,1-Diarylalkanes by NHC-Catalyzed Acylative Desymmetrization,” Lu, S.; Song, X.; Poh, S. B.; Yang, H.; Wong, M. W.;* Zhao, Y.* Chem. Eur. J. 2017, 23, 2275-2281(L.S. and S.X. contributed equally).

 

22.“Acid-Assisted Ru-Catalyzed Enantioselective Amination of 1,2-Diols through Borrowing Hydrogen,” Yang, L.-C.; Wang, Y.-N.; Zhang, Y.;* Zhao, Y.* ACS Catalysis, 2017, 7, 93-97.

 

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21.“Formal [3 + 2] cycloaddition of α-unsubstituted isocyanoacetates and methyleneindolinones: enantioselective synthesis of spirooxindoles,” Peng, X.-J.; Ho, Y. A.; Wang, Z.-P.; Shao, P.-L.;* Zhao, Y.;* He, Y.* Org. Chem. Front. 2017, 4, 81-85.

 

20.“Access to Acyclic (Z)-Enediynes via Alkyne Trimerization: Cooperative Bimetallic Catalysis Using Air as the Oxidant,” Lee, J. T. D.; Zhao, Y. Angew. Chem. Int. Ed. 2016, 55, 13872-13876.

 

19.“Stereoselective 1,6-Conjugate Addition/Annulation of Para-Quinone Methides with Vinyl Epoxides/Cyclopropanes,” Ma, C; Huang, Y.; Zhao, Y. ACS Catalysis, 2016, 6, 6408-6412 (M.C. and H.Y. contributed equally).

 

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18.“Asymmetric Transfer Hydrogenation of Imines using Alcohol:  Efficiency and Selectivity Are Affected by the Hydrogen Donor,” Pan, H.-J.; Zhang, Y.; Shan, C.; Yu, Z.; Lan, Y.*; Zhao, Y.* Angew. Chem. Int. Ed. 2016, 55, 9615-9619.

 

17. "Cobalt-Catalyzed Enantioselective Vinylation of Activated Ketones and Imines," Huang, Y.; Huang, R.-Z.; Zhao, Y. J. Am. Chem. Soc. 2016, 138, 6571-6576 (H. Y. and H. R.-Z. contributed equally).

 

16. "Catalyst-Enabled Diastereodivergent aza-Diels-Alder Reaction: Complementarity of N-Heterocyclic Carbene and Chiral Amine," Rong, Z. Q.; Wang, M.; Chow, C. H. E.; Zhao, Y. Chem. Eur. J. 2016, 22, 9483-9487 (R.Z.Q. and W.M. contributed equally).

 

15.“Iron-catalyzed transfer hydrogenation of imines assisted by an iron-based Lewis acid,” Pan, H.-J.; Ng, T. W.; Zhao, Y. Org. Biomol. Chem. 2016, 14, 5490-5493 (Invited article for “New Talent Issue”).

 

14.“Cobalt-Catalyzed Allylation of Heterobicyclic Alkenes: Ligand-Induced Divergent Reactivities,” Huang, Y.; Ma, C.; Lee, Y. X.; Huang, R.-Z. Zhao, Y. Angew. Chem. Int. Ed. 2015, 54, 13696-13700.

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13.“Iron-catalyzed amination of alcohols assisted by Lewis acid,” Pan, H.-J.; Ng, T. W.; Zhao, Y. Chem. Comm. 2015, 51, 11907–11910.

13

 

12. "Phase-Transfer-Catalyzed Enantioselective α-Hydroxylation of Acyclic and Cyclic Ketones with Oxygen," Sim, S. B. D.; Wang, M.; Zhao, Y. ACS Catal. 2015, 5, 3609-3612.

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11. "Dynamic Kinetic Asymmetric Amination of Alcohols: From A Mixture of Four Isomers to Diastereo- and Enantiopure a-Branched Amines," Rong, Z. Q.; Zhang, Y.; Chua, R. H. B.; Pan, H.-J.; Zhao, Y. J. Am. Chem. Soc. 2015, 137, 4944-4947 (R.Z.Q. and Z.Y. contributed equally).

11

 

10. "Catalytic Divergent Synthesis of 3H or 1H Pyrroles by [3+2] Cyclization of Allenoates with Activated Isocyanides," Liao, J.-Y.; Shao, P.-L.; Zhao, Y. J. Am. Chem. Soc. 2015, 137, 628-631 (L.J.Y. and S.P.L. contributed equally).

pyrrole

 

9. "Stereoselective Synthesis of e-Lactones or Spiro-Heterocycles through NHC-Catalyzed Annulation: Divergent Reactivity by Catalyst Control," Wang, M.; Rong, Z.-Q.; Zhao, Y. Chem. Comm. 2014, 50, 15309-15312 (W.M. and R.Z.Q. contributed equally).

9

 

8. "Kinetic Resolution of 1,1’-Biaryl-2,2’-Diols and Amino Alcohols through NHC-Catalyzed Atroposelective Acylation," Lu, S.; Poh, S. B.; Zhao, Y. Angew. Chem. Int. Ed. 2014, 53, 11041-11045.

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7. "Highly Diastereo- and Enantioselective Ag-Catalyzed Double [3+2] Cyclization of a-Imino Esters with Isocyanoacetate," Shao, P.-L.; Liao, J.-Y.; Ho, Y. A.; Zhao, Y. Angew. Chem. Int. Ed. 2014, 53, 5435-5439.

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This article was featured in Synfacts.

 

6. "Enantioselective Oxidation of 1,2-Diols with Quinine-derived Urea Organocatalyst," Rong, Z.-Q.; Pan, H.-J.; Yan, H.-L.; Zhao, Y. Org. Lett. 2014, 16, 208−211.

6

 

5. "Catalytic Enantioselective Amination of Alcohols by the Use of Borrowing Hydrogen Methodology: Cooperative Catalysis by Iridium and a Chiral Phosphoric Acid," Zhang, Y.; Lim, C.-S.; Sim, D. S. B.; Pan, H.-J.; Zhao, Y. Angew. Chem. Int. Ed. 2014, 53, 1399-1403.

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4. "Practical, Highly Stereoselective Allyl- and Crotylsilylation of Aldehydes Catalyzed by Readily Available Cinchona Alkaloid Amide," Huang, Y.; Yang, L.; Shao, P.; Zhao, Y. Chem. Sci. 2013, 4, 3275-3281.

2

 

3. Invited highlight: "Kinetic Resolution of 3-Hydroxy-3-Substituted Oxindoles through NHC-Catalyzed Oxidative Esterification," Lu, S.; Poh, S. B.; Siau, W.-Y.; Zhao, Y. Synlett, 2013, 24, 1165-1169.

2. “Kinetic Resolution of Tertiary Alcohols: Highly Enantioselective Access to 3-Hydroxy-3-Substituted Oxindoles,” Lu, S.; Poh, S. B.; Siau, W.-Y.; Zhao, Y. Angew. Chem. Int. Ed. 2013, 52, 1731-1734.

2

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1. Invited review: “Stereoselective Synthesis of Z-Alkenes,” Siau, W.-Y.; Zhang, Y.; Zhao, Y. Top. Curr. Chem. 2012, 327, 33-58.

1

 

 

Previous

 

 

Publications

7. “Preparation of Highly Pure Disubstituted E Olefins through Mo-Catalyzed Z-Selective Ethenolysis of Stereoisomeric Mixtures,” Marinescu, S. C.; Levine, D. S.; Zhao, Y.; Schrock, R. R.; Hoveyda, A. H. J. Am. Chem. Soc. 2011, 133, 11512-11514.

6. “Regiodivergent Reactions through Catalytic Enantioselective Silylation of Chiral Diols. Synthesis of Sapinofuranone A,” Rodrigo, J.; Zhao, Y.; Hoveyda, A. H.; Snapper, M. L. Org. Lett. 2011, 13, 3778-3781.

5.Endo-Selective Enyne Ring-Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes,” Zhao, Y.; Hoveyda, A. H.; Schrock, R. R. Org. Lett. 2011, 13, 784-787.

4. “Highly Z-Selective Metathesis Homocoupling of Terminal Olefins,” Jiang, A. J.; Zhao, Y.; Hoveyda, A. H.; Schrock, R. R. J. Am. Chem. Soc. 2009, 131, 16630-16631.

3. “Kinetic Resolution of 1,2-Diols through Highly Site- and Enantioselective Catalytic Silylation,” Zhao, Y.; Mitra, A. W.; Hoveyda, A. H.; Snapper, M. L. Angew. Chem. Int. Ed. 2007, 44, 8471-8474.

2. “Enantioselective Silyl Protection of Alcohols Catalysed by an Amino-Acid-Based Small Molecule,” Zhao, Y.; Rodrigo, J.; Hoveyda, A. H.; Snapper, M. L. Nature 2006, 443, 67-70.

1. “Proline-Based N-Oxides as Readily Available and Modular Chiral Catalysts. Enantioselective Reactions of Allyltrichlorosilane with Aldehydes,” Traverse, J. F.; Zhao, Y.; Hoveyda, A. H.; Snapper, M. L. Org. Lett. 2005, 7, 3151-3154.

 

Patents

2. “Highly Z-Selective Olefin Metathesis,” Schrock, R. R.; Hoveyda, A. H.; Jiang, A. J.; Zhao, Y.; Flook, M. M. Publication 2011, # US-2011-0077421-A1.

1. “Catalytic Enantioselective Silylations of Substrates,” Snapper M. L.; Hoveyda A. H.; Rodrigo, J.; Zhao, Y. PCT Int. Appl. 2007, # WO2007082026.